maleCNS

The complete central nervous system of an adult male Drosophila melanogaster: brain, both optic lobes and the ventral nerve cord, 164,587 traced neurons and 25,563,197 neuron-to-neuron connections carrying 125 million synapses.

Packed from the MaleCNS v1.0 flat-connectome export (HHMI Janelia FlyEM, Google Research and the Cambridge connectomics group; released 8 June 2026, published as Berg et al. 2026, Sexual dimorphism in the complete Drosophila male central nervous system connectome, Cell, doi:10.1016/j.cell.2026.08.015). The export used is the traced-only, minimum-confidence 0.5 connectivity table, with the curated body annotations (cell type, class, superclass, side, sexual dimorphism, fru/dsx expression) and the per-body consensus neurotransmitter prediction. Soma positions come from the annotation table's soma location in 8 nm voxels, converted to micrometres and centred; 139,741 neurons carry one, the rest sit at the origin with the has-soma flag clear.

Data license: CC-BY 4.0, https://male-cns.janelia.org/. The manifest carries the SHA-256 of each source file.

Sign convention: a neuron whose consensus transmitter is GABA, glutamate or histamine inhibits every target; every other transmitter excites (Shiu et al. 2024, Nature). Connection strengths are synapse counts; the wiring says which neurons reach which and how many synapses they make, and nothing about the efficacy of each synapse in a living fly.